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Search Results for " proto-oncogene c-met "

Targets Recommended: Apoptosis c-Met/HGFR

4

抑制剂 & 化合物

11

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T1963	Capmatinib NVP-INC280,INC-280,卡马替尼,INCB28060	Apoptosis; c-Met/HGFR	Apoptosis; Tyrosine Kinase/Adaptors
	Capmatinib (INCB28060) 是一种具有口服活性的，选择性的，ATP 竞争性的c-Met 激酶抑制剂，IC50值为0.13 nM。它有效抑制 c-Met 依赖性肿瘤细胞的增殖和迁移，可诱导细胞凋亡，有抗肿瘤活性。
T8825	Capmatinib 2HCl.H2O INCB28060 2HCl.H2O,INC-280 2HCl.H2O,NVP-INC280 2HCl.H2O	c-Met/HGFR	Tyrosine Kinase/Adaptors
	Capmatinib 2HCl.H2O (NVP-INC280 2HCl.H2O) 是一种具有潜在抗肿瘤活性的原癌基因 c-Met (HGFR) 的口服生物可利用抑制剂。
T3455	Merestinib LY2801653	Discoidin Domain Receptor (DDR); FLT; c-Met/HGFR; ROS; ROS Kinase	Angiogenesis; Immunology/Inflammation; Tyrosine Kinase/Adaptors
	Merestinib (LY2801653) 是一种有效的口服生物可利用的具有抗肿瘤活性的c-Met 抑制剂。
T71187	Foretinib phosphate
	Foretinib phosphate is an orally bioavailable small molecule with potential antineoplastic activity. MET/VEGFR2 inhibitor GSK1363089 binds to and selectively inhibits hepatocyte growth factor (HGF) receptor c-MET and vascular endothelial growth factor receptor 2 (VEGFR2), which may result in the inhibition of tumor angiogenesis, tumor cell proliferation and metastasis. The proto-oncogene c-MET has been found to be over-expressed in a variety of cancers.

化合物

Cat.No: T1963

Synonym: NVP-INC280,INC-280,卡马替尼,INCB28060

Target: Apoptosis, c-Met/HGFR

Capmatinib 2HCl.H2O

Cat.No: T8825

Synonym: INCB28060 2HCl.H2O,INC-280 2HCl.H2O,NVP-INC280 2HCl.H2O

Target: c-Met/HGFR

Cat.No: T3455

Synonym: LY2801653

Target: Discoidin Domain Receptor (DDR), FLT, c-Met/HGFR, ROS, ROS Kinase

Foretinib phosphate

Cat.No: T71187

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01896	HGFR/c-Met Protein, Mouse, Recombinant (His) MET proto-oncogene, re	Mouse	HEK293 Cells
	HGFR/c-Met Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 102 kDa and the accession number is EDL13881.1.
TMPY-01296	HGFR/c-Met Protein, Human, Recombinant (His) AUTS9,MET proto-oncogene...	Human	HEK293 Cells
	HGFR/c-Met Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 103 kDa and the accession number is A0A024R759.
TMPY-01895	HGFR/c-Met Protein, Mouse, Recombinant (hFc) c-Met,AI838057,MET proto...	Mouse	HEK293 Cells
	HGFR/c-Met Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 128 kDa and the accession number is A4FUV6.
TMPY-04379	HGFR/c-Met Protein, Human, Recombinant (aa 956-1390, His & GST) MET proto-oncogene, re	Human	Baculovirus Insect Cells
	HGFR/c-Met Protein, Human, Recombinant (aa 956-1390, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 76.8 kDa and the accession number is P08581-1.
TMPY-05607	HGFR/c-Met Protein, Human, Recombinant (His & Avi), Biotinylated MET proto-oncogene, re	Human	HEK293 Cells
	HGFR/c-Met Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 104.9 kDa and the accession number is A0A024R759.
TMPY-00718	HGFR/c-Met Protein, Human, Recombinant (His & hFc) DFNB97,RCCP2,AUTS9,MET proto<...	Human	HEK293 Cells
	HGFR/c-Met Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 129.5 kDa and the accession number is A0A024R759.
TMPY-05441	HGFR/c-Met Protein, Human, Recombinant (hFc) HGFR,DFNB97,RCCP2,AUTS9,c-Met...	Human	HEK293 Cells
	HGFR/c-Met Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 128.4 kDa and the accession number is A0A024R759.
TMPJ-00415	HGFR/c-Met Protein, Human, Recombinant (aa 25-932, His & Avi), Biotinylated SF receptor,HGF receptor,Scatter ...	Human	HEK293 Cells
	Hepatocyte growth factor receptor (HGF R) is a glycosylated receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. HGF R is synthesized as a single chain precursor which undergoes cotranslational proteolytic cleavage. Mature HGF R is a disulfide-linked dimer composed of a 50 kDa extracellular α chain and a 145 kDa transmembrane β chain. Proteolysis and alternate splicing generate additional forms of human HGF R which either lack of the kinase domai...
TMPK-01450	HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated KRAS1,MHC,K-RAS4B,KRAS,CFC2,K-RAS...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01456	HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi) KRAS2,NS,MHC,C-K-RAS,KRAS1,K-RAS2A,K-RAS2B...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01451	HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi) NS3,K-RAS4A,K-Ras 2,NS,KRAS1,RASK2,MHC,KI-RAS,KRAS,...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.

重组蛋白

HGFR/c-Met Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01896

Species: Mouse

Expression System: HEK293 Cells

HGFR/c-Met Protein, Human, Recombinant (His)

Cat.No: TMPY-01296

Species: Human

Expression System: HEK293 Cells

HGFR/c-Met Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-01895

Species: Mouse

Expression System: HEK293 Cells

HGFR/c-Met Protein, Human, Recombinant (aa 956-1390, His & GST)

Cat.No: TMPY-04379

Species: Human

Expression System: Baculovirus Insect Cells

HGFR/c-Met Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-05607

Species: Human

Expression System: HEK293 Cells

HGFR/c-Met Protein, Human, Recombinant (His & hFc)

Cat.No: TMPY-00718

Species: Human

Expression System: HEK293 Cells

HGFR/c-Met Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05441

Species: Human

Expression System: HEK293 Cells

HGFR/c-Met Protein, Human, Recombinant (aa 25-932, His & Avi), Biotinylated

Cat.No: TMPJ-00415

Species: Human

Expression System: HEK293 Cells

HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01450

Species: Human

Expression System: HEK293 Cells

HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01456

Species: Human

Expression System: HEK293 Cells

HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01451

Species: Human

Expression System: HEK293 Cells

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